NanoFibers for Nerve Fibers

Credit: Journal of NeuroscienceA new material has been developed that has been shown to heal spinal cord injuries in mice. The work has recently been published in the Journal of Neuroscience by Professor Samuel Stupp and his group at Northwestern University and describes a liquid material, which contains molecules that self-assemble into hollow, cylindrical nanofibers in vivo. These nanofibers then act as a scaffold by trapping cells, which facilitates growth of nerve fibers. The surface of the nanofibers also contains a material that inhibits the formation of scar tissue that can otherwise block nerve fibers and prevent their growth.

The liquid has been injected directly into the spinal cord of animals, restoring function to their previously paralyzed hind legs. The material then breaks down into nutrients in the body within three to eight weeks. I find these kinds of nanomaterials very exciting and worthwhile and can’t wait to see them in clinical use.